iVenomDB

Welcome to iVenomDB

Introduction

Insect venoms are important natural resources. They are valuable as lead compounds in pharmaceutical and agriculture.
Insect venom protein database (iVenomDB) is a database specializing in the sequence and structures of insect venom protein, contains 4847 protein sequence entries of 139 insect species. iVenomDB intends to provide a comprehensive platform of venom protein and online bioinformatic analysis.

Please Cite:
Chen, L. F., Lang, K., Zhang, B., Shi, J. M., Ye, X. H., Stanley, D. W., Fang, Q. and Ye, G. Y. (2023) iVenomDB: A manually curated database for insect venom proteins. Insect Science, 30(1), 264–266.

Statistics

Publications

Species	Publications	Year
Torymus sinensis	An integrated transcriptomic and proteomic approach to identify the main Torymus sinensis venom components	2021
Bombus ignitus	Anti-fibrinolytic activity of a metalloprotease inhibitor from bumblebee (Bombus ignitus) venom	2021
Aphidius gifuensis	Chromosome-level genome assembly of the aphid parasitoid Aphidius gifuensis using Oxford Nanopore sequencing and Hi-C technology	2021
Paraponera clavata	An Integrated Proteomic and Transcriptomic Analysis Reveals the Venom Complexity of the Bullet Ant Paraponera clavata	2020
Bracon nigricans	Venomics of the ectoparasitoid wasp Bracon nigricans	2020
Pachycrepoideus vindemmiae	Identification and Comparative Analysis of Venom Proteins in a Pupal Ectoparasitoid, Pachycrepoideus vindemmiae	2020
Aculeate wasps	Characterization of Venom Components and Their Phylogenetic Properties in Some Aculeate Bumblebees and Wasps	2020
Manica rubida	Venom Peptide Repertoire of the European Myrmicine Ant Manica rubida: Identification of Insecticidal Toxins	2020
Vespa velutina	Purification and molecular characterization of phospholipase, antigen 5 and hyaluronidases from the venom of the Asian hornet (Vespa velutina)	2020
Polistes dominula	Shedding Light on the Venom Proteomes of the Allergy-Relevant Hymenoptera Polistes dominula (European Paper Wasp) and Vespula spp. (Yellow Jacket)	2020
Ganaspis sp. 1	Bioinformatic analysis suggests potential mechanisms underlying parasitoid venom evolution and function	2020
Pteromalus puparum	Insight into the Functional Diversification of Lipases in the Endoparasitoid Pteromalus puparum (Hymenoptera: Pteromalidae) by Genome-scale Annotation and Expression Analysis	2020
Havinthus rufovarius	Crouching Tiger, Hidden Protein: Searching for Insecticidal Toxins in Venom of the Red Tiger Assassin Bug (Havinthus rufovarius)	2020
Vespa velutina	Development of an LC-MS multivariate nontargeted methodology for differential analysis of the peptide profile of Asian hornet venom (Vespa velutina nigrithorax): application to the investigation of the impact of collection period variation	2020
Dinoponera Quadriceps	Bottom-Up Proteomic Analysis of Polypeptide Venom Components of the Giant Ant Dinoponera Quadriceps	2019
Pimpla turionellae	Proteo-Transcriptomic Characterization of the Venom from the Endoparasitoid Wasp Pimpla turionellae with Aspects on Its Biology and Evolution	2019
Tetraponera aethiops	The Peptide Venom Composition of the Fierce Stinging Ant Tetraponera aethiops (Formicidae: Pseudomyrmecinae)	2019
Microplitis mediator	Insights into the venom protein components of Microplitis mediator, an endoparasitoid wasp	2019
Apis mellifera syriaca	First Characterization of The Venom from Apis mellifera syriaca, A Honeybee from The Middle East Region	2019
Myrmica rubra	Proteomic Analysis of the Venom from the Ruby Ant Myrmica rubra and the Isolation of a Novel Insecticidal Decapeptide	2019
Polybia paulista	Revisiting Polybia paulista wasp venom using shotgun proteomics - Insights into the N-linked glycosylated venom proteins	2019
Bombus pascuorum	Alteration of Bumblebee Venom Composition toward Higher Elevation	2019
Pristhesancus plagipennis	The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens	2018
Tetramorium bicarinatum	Deciphering the Molecular Diversity of an Ant Venom Peptidome through a Venomics Approach	2018
Tetrastichus brontispae	Venomics reveals novel ion transport peptide-likes (ITPLs) from the parasitoid wasp Tetrastichus brontispae	2018
Neoponera villosa	Peptidomic investigation of Neoponera villosa venom by high-resolution mass spectrometry: seasonal and nesting habitat variations	2018
Ooencyrtus telenomicida	First extensive characterization of the venom gland from an egg parasitoid: structure, transcriptome and functional role	2018
Microplitis mediator	A Metalloprotease Homolog Venom Protein From a Parasitoid Wasp Suppresses the Toll Pathway in Host Hemocytes	2018
Cotesia chilonis	Protein Discovery: Combined Transcriptomic and Proteomic Analyses of Venom from the Endoparasitoid Cotesia chilonis (Hymenoptera: Braconidae)	2017
Nasonia vitripennis	The Evolution of Venom by Co-option of Single-Copy Genes	2017
Diversinervus elegans	Unraveling the venom components of an encyrtid endoparasitoid wasp Diversinervus elegans	2017
Pristhesancus plagipennis	Melt With This Kiss: Paralyzing and Liquefying Venom of The Assassin Bug Pristhesancus plagipennis (Hemiptera: Reduviidae)	2017
Bombus sp.	Proteomic Characterization of the Venom of Five Bombus (Thoracobombus) Species	2017
Odontomachus monticola	Combined Venom Gland Transcriptomic and Venom Peptidomic Analysis of the Predatory Ant Odontomachus monticola	2017
Pachycondyla striata	Proteomic analysis of the venom of the predatory ant Pachycondyla striata (Hymenoptera: Formicidae)	2017
Polybia paulista	Wasp venomic: Unravelling the toxins arsenal of Polybia paulista venom and its potential pharmaceutical applications	2017
Cotesia vestalis and Diadromus collaris	Comparative transcriptome analysis of venom glands from Cotesia vestalis and Diadromus collaris, two endoparasitoids of the host Plutella xylostella	2017
Xylocopa appendiculata circumvolans	Peptidomic analysis of the venom of the solitary bee Xylocopa appendiculata circumvolans	2017
Pteromalus puparum	A Venom Serpin Splicing Isoform of the Endoparasitoid Wasp Pteromalus puparum Suppresses Host Prophenoloxidase Cascade by Forming Complexes with Host Hemolymph Proteinases	2017
Pteromalus puparum	Insights into the venom composition and evolution of an endoparasitoid wasp by combining proteomic and transcriptomic analyses	2016
Toxoneuron nigriceps	Identification of major Toxoneuron nigriceps venom proteins using an integrated transcriptomic/proteomic approach	2016
Scleroderma guani	Deciphering the main venom components of the ectoparasitic ant-like bethylid wasp, Scleroderma guani	2016
Neoponera villosa	Analysis of Protein Composition and Bioactivity of Neoponera villosa Venom (Hymenoptera: Formicidae)	2016
Vespa tropica and Vespa affinis	Comparative proteomic analysis of two wasps venom, Vespa tropica and Vespa affinis	2016
Aenasius arizonensis	De novo sequencing and transcriptome analysis of venom glands of endoparasitoid Aenasius arizonensis (Girault) (=Aenasius bambawalei Hayat) (Hymenoptera, Encyrtidae)	2016
Bracon hebetor	De novo sequencing and transcriptome analysis of female venom glands of ectoparasitoid Bracon hebetor (Say.) (Hymenoptera: Braconidae)	2016
Megastigmus spermotrophus	Transcriptome analysis provides insight into venom evolution in a seed-parasitic wasp, Megastigmus spermotrophus	2016
Psyttalia lounsburyi and P. concolor	Comparative venomics of Psyttalia lounsburyi and P. concolor, two olive fruit fly parasitoids: a hypothetical role for a GH1 β-glucosidase	2016
Leptomastix dactylopii	Identification of two arginine kinase forms of endoparasitoid Leptomastix dactylopii venom by bottom up-sequence tag approach	2015
Pteromalus puparum	A Venom Gland Extracellular Chitin-Binding-Like Protein from Pupal Endoparasitoid Wasps, Pteromalus Puparum, Selectively Binds Chitin	2015
Vespa velutina	Deciphering the venomic transcriptome of killer-wasp Vespa velutina	2015
Anisopteromalus calandrae	Venom gland components of the ectoparasitoid wasp, Anisopteromalus calandrae	2015
Nasonia vitripennis	A new approach for investigating venom function applied to venom calreticulin in a parasitoid wasp	2015
Aphidius ervi	Identification of the main venom protein components of Aphidius ervi, a parasitoid wasp of the aphid model Acyrthosiphon pisum	2014
Apis mellifera	Exploring the hidden honeybee (Apis mellifera) venom proteome by integrating a combinatorial peptide ligand library approach with FTMS	2014
Vespa affinis	Proteome and allergenome of Asian wasp, Vespa affinis, venom and IgE reactivity of the venom components	2014
Tetramorium bicarinatum	De Novo sequencing and transcriptome analysis for Tetramorium bicarinatum: a comprehensive venom gland transcriptome analysis from an ant species	2014
Dinoponera quadriceps	Transcriptome analysis in venom gland of the predatory giant ant Dinoponera quadriceps: insights into the polypeptide toxin arsenal of hymenopterans	2014
Leptopilina boulardi and Leptopilina heterotoma	Integrative approach reveals composition of endoparasitoid wasp venoms	2013
Leptopilina boulardi and Leptopilina heterotoma	Extensive inter- and intraspecific venom variation in closely related parasites targeting the same host: the case of Leptopilina parasitoids of Drosophila	2013
Leptopilina boulardi and Leptopilina heterotoma	Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity	2013
Apis mellifera	Proteome and phosphoproteome of Africanized and European honeybee venoms	2013
Apis mellifera	Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland	2013
Tetramorium bicarinatum	Profiling the venom gland transcriptome of Tetramorium bicarinatum (Hymenoptera: Formicidae): the first transcriptome analysis of an ant species	2013
Polybia paulista	Hyaluronidase from the venom of the social wasp Polybia paulista (Hymenoptera, Vespidae): Cloning, structural modeling, purification, and immunological analysis	2013
Vespa tropica	Antimicrobial peptides from the venom gland of the social wasp Vespa tropica	2013
Apis mellifera	Extending the honey bee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5	2013
Dinoponera quadriceps	Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil	2013
Leptopilina heterotoma	Partial venom gland transcriptome of a Drosophila parasitoid wasp, Leptopilina heterotoma, reveals novel and shared bioactive profiles with stinging Hymenoptera	2013
Solenopsis invicta	Proteomic view of the venom from the fire ant Solenopsis invicta Buren	2012
Polybia paulista	Proteomic characterization of the multiple forms of the PLAs from the venom of the social wasp Polybia paulista	2011
Pteromalus puparum	Proteomic analysis of the venom from the endoparasitoid wasp Pteromalus puparum (Hymenoptera: Pteromalidae)	2010
Polybia paulista	Profiling the proteome of the venom from the social wasp Polybia paulista: a clue to understand the envenoming mechanism	2010
Apis mellifera	Two novel proteins expressed by the venom glands of Apis mellifera and Nasonia vitripennis share an ancient C1q-like domain	2010
Chelonus inanitus	The venom composition of the parasitic wasp Chelonus inanitus resolved by combined expressed sequence tags analysis and proteomic approach	2010
Nasonia vitripennis	Insights into the venom composition of the ectoparasitoid wasp Nasonia vitripennis from bioinformatic and proteomic studies	2010
Pimpla hypochondriaca	Identification, cloning and expression of a second gene (vpr1) from the venom of the endoparasitic wasp, Pimpla hypochondriaca that displays immunosuppressive activity	2010
Leptopilina boulardi	A serpin from the parasitoid wasp Leptopilina boulardi targets the Drosophila phenoloxidase cascade	2009
Eulophus pennicornis	A venom metalloproteinase from the parasitic wasp Eulophus pennicornis is toxic towards its host, tomato moth (Lacanobia oleracae)	2009
Pimpla hypochondriaca	Cloning and expression of the gene for an insect haemocyte anti-aggregation protein (VPr3), from the venom of the endoparasitic wasp, Pimpla hypochondriaca	2009
Microctonus hyperodae	The constituents of Microctonus sp. parasitoid venoms	2008
Pteromalus puparum	Isolation and characterization of an immunosuppressive protein from venom of the pupa-specific endoparasitoid Pteromalus puparum	2008
Aphidius ervi	A gamma-glutamyl transpeptidase of Aphidius ervi venom induces apoptosis in the ovaries of host aphids	2007
Myrmecia pilosula	Proteomic analysis of Myrmecia pilosula (jack jumper) ant venom	2006
Cotesia rubecula	A calreticulin-like protein from endoparasitoid venom fluid is involved in host hemocyte inactivation	2006
Apis mellifera	The protein composition of honeybee venom reconsidered by a proteomic approach	2005
Dinocampus coccinellae	Molecular cloning and analysis of a novel teratocyte-specific carboxylesterase from the parasitic wasp, Dinocampus coccinellae	2005
Pimpla hypochondriaca	Hydrolase activity in the venom of the pupal endoparasitic wasp, Pimpla hypochondriaca	2005
Leptopilina boulardi	Haemocyte changes in D. Melanogaster in response to long gland components of the parasitoid wasp Leptopilina boulardi: a Rho-GAP protein as an important factor	2005
Leptopilina boulardi	A RhoGAP protein as a main immune suppressive factor in the Leptopilina boulardi (Hymenoptera, Figitidae)-Drosophila melanogaster interaction	2005
Agelaiapallipes pallipes	Structural characterization of novel chemotactic and mastoparan peptides from the venom of the social wasp Agelaiapallipes pallipes by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry	2004
Agelaia pallipes	Structural and biological characterization of two novel peptides from the venom of the neotropical social wasp Agelaia pallipes pallipes	2004
Cotesia rubecula	Negative regulation of prophenoloxidase (proPO) activation by a clip-domain serine proteinase homolog (SPH) from endoparasitoid venom	2004
Euplectrus separatae	The function of a trypsin-like enzyme in the saliva of Euplectrus separatae larvae	2004
Cotesia rubecula	A serine proteinase homolog venom protein from an endoparasitoid wasp inhibits melanization of the host hemolymph	2003
Cotesia rubecula	Isolation and characterization of a novel venom protein from an endoparasitoid, Cotesia rubecula (Hym: Braconidae)	2003
Pimpla hypochondriaca	Analysis of venom constituents from the parasitoid wasp Pimpla hypochondriaca and cloning of a cDNA encoding a venom protein	2002
Pimpla hypochondriaca	Purification of pimplin, a paralytic heterodimeric polypeptide from venom of the parasitoid wasp Pimpla hypochondriaca, and cloning of the cDNA encoding one of the subunits	2002
Eupelmus orientalis	Physiological and Biochemical Analysis of Factors in the Female Venom Gland and Larval Salivary Secretions of the Ectoparasitoid Wasp Eupelmus orientalis	1997
Bracon hebetor	Purification and characterization of insecticidal toxins from venom glands of the parasitic wasp, Bracon hebetor	1994