Venom Protein Card
Accession: Add00186 Kunitz-type serine protease inhibitor Bt-KTI [Bombus terrestris]
Basic info
| Organism | Bombus terrestris |
| Taxonomy | Insecta > Hymenoptera > Apidae > Bombus > Bombus terrestris |
| Protein Description | Kunitz-type serine protease inhibitor Bt-KTI |
| Mass Weight | 9020.36 Da |
| Isoelectric Point | 6.23 |
| Expression | Highly expressed in venom gland |
Annotation
| Function | Serine protease inhibitor that inhibits plasmin (Ki=2.01 nM) and trypsin. Acts as an antifibrinolytic agent. | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Signal Peptide | 1..24 | 24 |
| Chain | 25..82 | 58 |
Sequence
Publication
| 1. |
Qiu Y., Lee K.S., Choo Y.M., Kong D., Yoon H.J., Jin B.R.; "Molecular cloning and antifibrinolytic activity of a serine protease inhibitor from bumblebee (Bombus terrestris) venom."; Toxicon 63:1-6(2013). |
| 2. |
Kim S.R., Yoon H.J., Park K.-H., Yun E.-Y., Kim I., Jin B.-R., Hwang J.-S.; "Molecular cloning of cDNA for kazal-type proteinase inhibitior from the bumblebee Bombus terrestris."; Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases. |