Venom Protein Card
Accession: Pre00065 Venom phospholipase A2 [Bombus ignitus]
Basic info
| Organism | Bombus ignitus |
| Taxonomy | Insecta > Hymenoptera > Apidae > Bombus > Bombus ignitus |
| Protein Description | Venom phospholipase A2 |
| Mass Weight | 20841.47 Da |
| Isoelectric Point | 6.04 |
| Expression | Highly expressed in venom gland |
Annotation
| Function | PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.Bi-PLA2 binds at the cell membrane, hydrolyzes cell membrane phospholipids and induces apoptotic cell death. | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Signal Peptide | 1..21 | 21 |
| Chain | 22..180 | 159 |
Sequence
3D Structure
Not available now!
Publication
| 1. |
Xin Y., Choo Y.M., Hu Z., Lee K.S., Yoon H.J., Cui Z., Sohn H.D., Jin B.R.; "Molecular cloning and characterization of a venom phospholipase A2 from the bumblebee Bombus ignitus."; Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 154:195-202(2009). |