Venom Protein Card
Accession: Pre00066 Venom metalloprotease inhibitor [Bombus ignitus]
Basic info
| Organism | Bombus ignitus |
| Taxonomy | Insecta > Hymenoptera > Apidae > Bombus > Bombus ignitus |
| Protein Description | Venom metalloprotease inhibitor |
| Mass Weight | 11545.3 Da |
| Isoelectric Point | 8.65 |
| Expression | Highly expressed in venom gland |
Annotation
| Function | BiVMPI is a metalloprotease inhibitor in bumblebee venom. It exhibited inhibitory activity against human plasmin but did not show inhibitory activity against thrombin or elastase. BiVMPI also acts as an anti-fibrinolytic agent | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Signal Peptide | 1..21 | 21 |
| Chain | 22..105 | 84 |
Sequence
3D Structure
Not available now!
Publication
| 1. |
Kim BY, Lee KS, Lee KY, Yoon HJ, Jin BR.; Anti-fibrinolytic activity of a metalloprotease inhibitor from bumblebee (Bombus ignitus) venom.; Comp Biochem Physiol C Toxicol Pharmacol 2021 Jul;245:109042. |