iVenomDB

Basic info

Organism	Osmia rufa
Taxonomy	Insecta > Hymenoptera > Megachilidae > Osmia > Osmia rufa
Protein Description	Disintegrin and metalloproteinase domain-containing protein 19
Mass Weight	176675.48 Da
Isoelectric Point	8.83
Expression	Highly expressed in venom gland

Annotation

Pfam

PF01562

Pep_M12B_propep

Features

Feature key	Position	Length
Signal Peptide	1..38	38
Chain	39..1628	1590

Cross-Reference

NCBI Nucleotide	XM_029185063.1
NCBI Protein	XP_029040896.1

Sequence

CDS[Download]

ATGCCAAGTGATATCCGGTGCTCGAATCCACGATGGATCGTCGGTGGTGTGACGGTGCAGTGCAAATTGGTGCTGATTTTGGTGCTGCTCGCAATCCTACCTGACGTGTACACCGAGAGCCACGGACCGTCCCCAGATTTCAGCAGACACACGCTGATCAGACCACGAGTGTATCACGGAAGGACCAAGCGGCAGATCTCGTCCAGCAAAGAAAACGACGTGGAGCACGCGGATGTGTTGACGGTGGGCTTCGAACTGGACGGGGTGAAACGCGTCCTGGATCTCAGGCTGAACACCGATCTCATCCCGGTCGGATACCAGCAACGTCATCAGCATCGCGGCACCTACAAAGAGCACCTACCGTCGAAAAATGAACTCTGCCACTATCAAGGTAGCGTTCGAGACGTTCCTGGCTCCTGGGTAGCATTGTCTACGTGCAGAGGATTGCGCGGCGTTGTTTTCGACGGCGAGAACCTTCACCACATTCACCCGGAGAAGGAATCCTTGGAGTCGAACCATTACGTCTACAATCATAAGGATCTCGTCGCCAATCACACCTGCGGTTACGAAGGAACGCCGCACCATGTACCCGACCATGAACACCGCAAGATCGTCAACAGAGCTACCAGGCACAAAAGAGCGACCGAGGTGATTCGAGGACCCTACAACGCGAACAGACATTCCAGATACGTGGAGTTGGTGCTGGTGATCGATAAGAAGGAGTACATTGCTCTCGACGAGAACCTGGACAAGGTGTATCAACACTGCAAGGACATTGCAAACATCATCAATGCTTTGTACATGCCGCTGAACATATTCATCGCCCTGGTCGGTGTTCAAGTTTGGACTGACACGGACGAGATCACTCTGTCTACAAACGGGGACACCACCCTCTCGAATTTCCTTCGTTACAGGAGAGAGAAGCTAGTCCAAGACATGCCGAACGACAACGCCCAACTGTTAACGCGAATCACCTTCGGCGGAGGCGTGGTAGGAAAAGCGCTTAAGGGACCAATATGTACGTACGAATTTTCCGGTGGGGTCTCGATGGATCACTCGAACGTCGTTGGATTAGTGGCGGCCACCGTGGCTCATGAAATGGGTCACAATTTCGGCATGGAACACGATTCCGCCGATTGCGAATGCCCTGAAGAGAAATGCATCATGGCATCGTCGAGCGGCTCCTCGGGACCGACACATTGGTCGACGTGTTCCCTGGAACATCTGGCGTTGGCCTTCGAACACGGCATGGATTACTGCCTGAGGAACAAACCGCCGAAGCTTTTCGACAGTCCAATTTGCGGCAACGGCTTCGTCGAACCAGGGGAACAATGCGACTGTGGCTTGAAGGAGAACTGCGACAATCCTTGTTGCAACGTAACCACCTGCATGTTGCACAGCAACGCTAGCTGCGCTACCGGAGAGTGTTGCGATCTGAAGACCTGTCGACCGAAGAGCGCTGGCACCGAATGCAGAAGCGCGGAACACGAATGCGATTTGCCGGAGTATTGCACCGGACAGAGCGAATACTGTCCGGTGGACGTGTTCAAGATGGACGGAGAATCGTGCAGTATGGGAAAAGCTTTCTGCTATCAAGGCTCGTGCAGGACGCACAACGATCAGTGCAAATTACTCTGGGGTCCTACGGGTTCGTCGTCCGACGCCCAGTGCTACGACATGAACAACAGGGGCACGAAACATGGGAACTGCGGCTACAACAGGGTCGCATCCAGCTACGTCAAGTGCACCGACGAGAATCTTCTTTGCGGGATGCTTCATTGCAAACACCTGAACGAGAGGCTAGAGTTCGGCATGGAATCCGTGGCGATACTAAGTCACTCGTTCATCAACAACGGGGGGAAGATTATACCTTGTCGTTCGGCTATCGTGGATCTGGGATTAAATCAGGTAGACCCTGGTCTTGCTCCAGACGGCGCCAAGTGTGCACCTGGGAAGATGTGCGTCAATCAGAAGTGCATGACGGTTGCCGATCTACGCGCATCCGTGTCCGGAGGGAAAGCGTGTCCCAATAATTGCGGAGGCAACGGTGTGTGCAACAGTTTGGGACACTGTCACTGCAGTCGTGGCTTCCGGCCGCCCGATTGCACTCAACCTGGCGTCGGTGGTTCCGAGGACAGCGGTCCAGCCGAGGATCCAAATGCGAGAAACGACTTTATAATGGCTCTGTACATTATCTTCTTGGGCATAGTACCGATGATTGCCCTGTCCTCGTTCGGCGTTTGGTACGTGAGAAACCCTGGCCAACACTGGAAAAAAGGAATGATGTCAACGACCGATCGCGGCCACAACGGACTATCCATCAAAACGATCGATCGTTCCAGTCCTTTGCCTCGTAGCATCGAAACGATCGATTCTAGGCTGAGCCAAGATCCAGCGTGCGCGAGCTTGTTGCCGAAAGCCCAACCGGACAAGCCTTACAACAATAACCTGTTCGGCCAGTTCAAAGGCTTCACGATCACCCCGATCAAGAGTCAAACGAAAACACCTGAGCCGAATAAACCGGCACCACCTCCGCCTACGATCCCAACCGTAGCCATCAAAACCAACATCAAGACTCTCCCGAAGAATAATCCGTCGAGAAGCTCTTTATTGAACACGACGTCTAGCTTCAACGATCCATCCGTTGCGCCAACTCTGCCGCCTTTGAATCCAGGCTGCACCGCCCGTCCTCTGATCAGTAGTCCGGTGCTGGCAGCTACCACCTGCACCTCCGTGGAGTTAGTGTCTCCCAAGACCTCCACTAGACCTCCTGATGGACCCACCAGGCCAGCTCCGGCTCCTCCTCTTTCCAACGATATCCAAAAACCTCCCAGACCCAACAGTACACCCTTGACAAACGTCCTGGTGCCTGAACCCGTCGAAAAGAAAGCCGACAAGAGCGGTACCCTGAACAGATTAGCCAACATGCTTCGACCAAACTCCGGTATCATAAAGGTGGGACTGCAAGCGTCCCAGAAAGACGAGAAGAACACGAATTCTTTACCTAGAACGCAGCACCTTAAAGCGAACAAGGTGATCGATAAAGAAATCTTAAGGAACTTGGAGATCTCCAACCCTATCCCTCAGAAGGAGATCGAGATACCCACACCAGCCATCTCCGTAATCCCTGCCGCTGATACGGATAAGAAAAACGTGGTGCTACGGGCTCAGTCGATGAGGGACAACAAGGTCACACCCAGACCAACGATCCAAACCTTTGGATCCATGAGACAGACGACACCGGTCAAGAGACCAACGAGTATTCCAGCTAGTACCAGACCCACTGCTCCACCTCCAGGACCTCCTACATCCACGGCCATCACCACGGACAAGATCAACGAGACAGGGAAGATTCCTGGGCTACCCGGTTACCAAACTCCGCAAGTGAAGAATATGCAAAAGGTAGTGGACAATGCTTACGACGACTGCATGAATCTCGTCTCTGACTCGTCTTTGACTAAGATCACCGAAGAATCGCCAACGAACGATAATATTTACGCTGTCATAGAGGAGGCTGTTCCCGAGAAGAATCGAAAGAATCCGGAATTGGAGAAGCAGGTCGACAACGAGTACAAACAACCGAAACGCGTCGAGACAACGTCCAACTCTGCTGGATTAGAGTCGATGGGTCTGTTGTCGGAGATCGTATCGGAGATATCGAATCGTAACTTTGATTCCATATACTCGACCGCCACACTGAAGAAGGGACAAGAGGCTGAGAATTCGAAGAACATGGAAGACTTGGGCTCGAACAGTTCCCTAGGCGCTTACGTGAACTCGAACCACTACAAATCACCGGGCAGCATTTATTCGAATTCTACCTCCGGCAAGTTCAACTCCTCCAGTTCGACGACCAGTTCGGGCTACTTGAATCCTTCGGCGTTGAACGTGCCGCAGCAACAGTCGAACAAACTCGTGCCAGACGCGAAATCGTTGAACAAAAGTAAACCAGTGTCTCTGAGTTCAACGAACCCGAATTTGAACGACGAGATATCGAAAGAGCTCGGTATGAAACCGGCGGAAGAGGTCGTGCACCGTAAGCCACTCGCTCCTCTGAAAACTCGTGGCATTCAACGTGCCTCGACGAACTCGAAGAGCGAGGAGGACACGGTCGACGGTAAGGAACAACCGTTGAAACCACCTCTTGGAAGAACAAAAACCCCACCGAACATCAGAACGTCGAAAGACAGCAGGCAAAGCGTGGACACCGCCTCAAAGTCTAAACAGGGAACTAAACAGAGTTCAAACTTGGATACAGTGAGCCAAGATTCAGAGACTAAAAGTAATAAGAACAGCACCGGTAGCTTGGATAAGGATTCTCACAATAAATTATCCATGAAAACTGTGCCTTGTAGTCCTAAGGATAACGGGGGAAGGTTGAACAGCCCTGATTTAGTGTCTAGTTGTTCGAATTCCAACCAAAACAGTACAAAATCACCGGATGTTCTTGGAAACAATCCAAAGCTAAATTTACAGCCGAAGAATGTTCAAAAAACGCCGACGCTTCCTCGAGGAAACGCCAAGGCAACGTCCACGCCGCCAAAGCCGTCGAACGTTGTCTCCAAAGGTACCGGTCCCCCTTTGGAGAAAAAGAAACCGTTTTCGGTCGGTGGTAACGTTAACGTCACCAAATCATTATCAACGACCGCGAAGGATGGAACGACGAAGAGCGCGTTGTCGAAATCGAATCAGAAAACGGAAACGAAGACCGGAGATTTAGGAACGAAGACGAACGCGGTGCAAAGGGCAGCTAGCAGCAAATCGAACGTGGCGTCTCTGCAGCAAAAATTCGAGGCCAACAGAAACGTGAACGCGTCGAGGACGATACCTAGTGTACACAAAAAGACTGTCGGGAAGACGACGGAAACTGCTGGTGTTAAAAAGTGA

Protein[Download]

MPSDIRCSNPRWIVGGVTVQCKLVLILVLLAILPDVYTESHGPSPDFSRHTLIRPRVYHGRTKRQISSSKENDVEHADVLTVGFELDGVKRVLDLRLNTDLIPVGYQQRHQHRGTYKEHLPSKNELCHYQGSVRDVPGSWVALSTCRGLRGVVFDGENLHHIHPEKESLESNHYVYNHKDLVANHTCGYEGTPHHVPDHEHRKIVNRATRHKRATEVIRGPYNANRHSRYVELVLVIDKKEYIALDENLDKVYQHCKDIANIINALYMPLNIFIALVGVQVWTDTDEITLSTNGDTTLSNFLRYRREKLVQDMPNDNAQLLTRITFGGGVVGKALKGPICTYEFSGGVSMDHSNVVGLVAATVAHEMGHNFGMEHDSADCECPEEKCIMASSSGSSGPTHWSTCSLEHLALAFEHGMDYCLRNKPPKLFDSPICGNGFVEPGEQCDCGLKENCDNPCCNVTTCMLHSNASCATGECCDLKTCRPKSAGTECRSAEHECDLPEYCTGQSEYCPVDVFKMDGESCSMGKAFCYQGSCRTHNDQCKLLWGPTGSSSDAQCYDMNNRGTKHGNCGYNRVASSYVKCTDENLLCGMLHCKHLNERLEFGMESVAILSHSFINNGGKIIPCRSAIVDLGLNQVDPGLAPDGAKCAPGKMCVNQKCMTVADLRASVSGGKACPNNCGGNGVCNSLGHCHCSRGFRPPDCTQPGVGGSEDSGPAEDPNARNDFIMALYIIFLGIVPMIALSSFGVWYVRNPGQHWKKGMMSTTDRGHNGLSIKTIDRSSPLPRSIETIDSRLSQDPACASLLPKAQPDKPYNNNLFGQFKGFTITPIKSQTKTPEPNKPAPPPPTIPTVAIKTNIKTLPKNNPSRSSLLNTTSSFNDPSVAPTLPPLNPGCTARPLISSPVLAATTCTSVELVSPKTSTRPPDGPTRPAPAPPLSNDIQKPPRPNSTPLTNVLVPEPVEKKADKSGTLNRLANMLRPNSGIIKVGLQASQKDEKNTNSLPRTQHLKANKVIDKEILRNLEISNPIPQKEIEIPTPAISVIPAADTDKKNVVLRAQSMRDNKVTPRPTIQTFGSMRQTTPVKRPTSIPASTRPTAPPPGPPTSTAITTDKINETGKIPGLPGYQTPQVKNMQKVVDNAYDDCMNLVSDSSLTKITEESPTNDNIYAVIEEAVPEKNRKNPELEKQVDNEYKQPKRVETTSNSAGLESMGLLSEIVSEISNRNFDSIYSTATLKKGQEAENSKNMEDLGSNSSLGAYVNSNHYKSPGSIYSNSTSGKFNSSSSTTSSGYLNPSALNVPQQQSNKLVPDAKSLNKSKPVSLSSTNPNLNDEISKELGMKPAEEVVHRKPLAPLKTRGIQRASTNSKSEEDTVDGKEQPLKPPLGRTKTPPNIRTSKDSRQSVDTASKSKQGTKQSSNLDTVSQDSETKSNKNSTGSLDKDSHNKLSMKTVPCSPKDNGGRLNSPDLVSSCSNSNQNSTKSPDVLGNNPKLNLQPKNVQKTPTLPRGNAKATSTPPKPSNVVSKGTGPPLEKKKPFSVGGNVNVTKSLSTTAKDGTTKSALSKSNQKTETKTGDLGTKTNAVQRAASSKSNVASLQQKFEANRNVNASRTIPSVHKKTVGKTTETAGVKK

3D Structure

Not available now!

Publication

1.	Beadle K, Singh KS, Troczka BJ, Randall E, Zaworra M, Zimmer CT, Hayward A, Reid R, Kor L, Kohler M, Buer B, Nelson DR, Williamson MS, Davies TGE, Field LM, Nauen R, Bass C.; Genomic insights into neonicotinoid sensitivity in the solitary bee Osmia bicornis.; PLoS Genet 2019 Feb 4;15(2):e1007903.

Venom Protein Card