Venom Protein Card


Accession: Pre02153    Mastoparan-like peptide 12c   [Vespa magnifica]

Basic info
Organism Vespa magnifica
Taxonomy Insecta > Hymenoptera > Vespidae > Vespa > Vespa magnifica
Protein Description Mastoparan-like peptide 12c
Mass Weight 3982.56 Da
Isoelectric Point 4.53
Expression Highly expressed in venom gland
Annotation
Function Shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E.coli ATCC 25922 (MIC=6.0 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=3.0 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=12 ug/ml).
Pfam
PF08249 Mastoparan
Features
Feature key Position Length
Signal Peptide 1..25 25
Peptide 26..39 14
Cross-Reference
NCBI Nucleotide DQ865260.1
NCBI Protein ABI94579.1
UniProt A0SPI0
Sequence
ATGAGTGCCGAAGCTTTAGCTGACCCAAAAGCTGATCCATTAGCTGGTCCAAATCCTGATGCTGATCCAGAAGCAATAAACCTGAAGGCTATTGCAGCATTGGCTAAGAAACTATTAGGTTAA
MSAEALADPKADPLAGPNPDADPEAINLKAIAALAKKLLG

3D Structure
Publication
1. Xu X., Yang H., Yu H., Li J., Lai R.;
"The mastoparanogen from wasp.";
Peptides 27:3053-3057(2006).