Venom Protein Card


Accession: Pre02155    Mastoparan-like peptide 12a   [Vespa magnifica]

Basic info
Organism Vespa magnifica
Taxonomy Insecta > Hymenoptera > Vespidae > Vespa > Vespa magnifica
Protein Description Mastoparan-like peptide 12a
Mass Weight 1556.96 Da
Isoelectric Point 10.3
Expression Highly expressed in venom gland
Annotation
Function Mast cell degranulating peptide. Has little hemolytic activity. Shows antimicrobial activity against the Gram-negative bacteria E.coli ATCC 25922 (MIC=7.5 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=3.7 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=3.7 ug/ml).
Pfam
PF08249 Mastoparan
Features
Feature key Position Length
Peptide 1..14 14
Cross-Reference
UniProt P0C1M4
Sequence
INWKGIAAMAKKLL

3D Structure
Publication
1. Xu X., Li J., Lu Q., Yang H., Zhang Y., Lai R.;
"Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.";
Toxicon 47:249-253(2006).
2. Xu X., Yang H., Yu H., Li J., Lai R.;
"The mastoparanogen from wasp.";
Peptides 27:3053-3057(2006).