Venom Protein Card


Accession: Pre02247    Mastoparan-X   [Vespa xanthoptera]

Basic info
Organism Vespa xanthoptera
Taxonomy Insecta > Hymenoptera > Vespidae > Vespa > Vespa xanthoptera
Protein Description Mastoparan-X
Mass Weight 1556.96 Da
Isoelectric Point 10.3
Expression Highly expressed in venom gland
Annotation
Function Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.
Pfam
PF08249 Mastoparan
Features
Feature key Position Length
Peptide 1..14 14
Cross-Reference
UniProt P01515
Sequence
INWKGIAAMAKKLL

3D Structure
Publication
1. Hirai Y., Kuwada M., Yasuhara T., Yoshida H., Nakajima T.;
"A new mast cell degranulating peptide homologous to mastoparan in the venom of Japanese hornet (Vespa xanthoptera).";
Chem. Pharm. Bull. 27:1945-1946(1979).
2. Wakamatsu K., Okada A., Miyazawa T., Ohya M., Higashijima T.;
"Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide.";
Biochemistry 31:5654-5660(1992).
3. Kusunoki H., Wakamatsu K., Sato K., Miyazawa T., Kohno T.;
"G protein-bound conformation of mastoparan-X: heteronuclear multidimensional transferred nuclear overhauser effect analysis of peptide uniformly enriched with 13C and 15N.";
Biochemistry 37:4782-4790(1998).