Venom Protein Card
Accession: Pre02257 Mastoparan-L [Vespula lewisii]
Basic info
| Organism | Vespula lewisii |
| Taxonomy | Insecta > Hymenoptera > Vespidae > Vespula > Vespula lewisii |
| Protein Description | Mastoparan-L |
| Mass Weight | 1479.89 Da |
| Isoelectric Point | 10.3 |
| Expression | Highly expressed in venom gland |
Annotation
| Function | Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C. May be able to switch from an in-plane to a transmembrane orientation in lipid bilayers. | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Peptide | 1..14 | 14 |
Sequence
Publication
| 1. |
Hirai Y., Yasuhara T., Yoshida H., Nakajima T., Fujino M., Kitada C.; "A new mast cell degranulating peptide 'mastoparan' in the venom of Vespula lewisii."; Chem. Pharm. Bull. 27:1942-1944(1979). |
| 2. |
Hori Y., Demura M., Iwadate M., Ulrich A.S., Niidome T., Aoyagi H., Asakura T.; "Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers."; Eur. J. Biochem. 268:302-309(2001). |