Venom Protein Card
Accession: Pre02373 Mastoparan-X [Vespa simillima]
Basic info
| Organism | Vespa simillima |
| Taxonomy | Insecta > Hymenoptera > Vespidae > Vespa > Vespa simillima |
| Protein Description | Mastoparan-X |
| Mass Weight | 1556.96 Da |
| Isoelectric Point | 10.3 |
| Expression | Highly expressed in venom gland |
Annotation
| Function | Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C. | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Peptide | 1..14 | 14 |
Sequence
3D Structure
Not available now!
Publication
| 1. |
Hirai Y., Kuwada M., Yasuhara T., Yoshida H., Nakajima T.; "A new mast cell degranulating peptide homologous to mastoparan in the venom of Japanese hornet (Vespa xanthoptera)."; Chem. Pharm. Bull. 27:1945-1946(1979). |
| 2. |
Wakamatsu K., Okada A., Miyazawa T., Ohya M., Higashijima T.; "Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide."; Biochemistry 31:5654-5660(1992). |
| 3. |
Kusunoki H., Wakamatsu K., Sato K., Miyazawa T., Kohno T.; "G protein-bound conformation of mastoparan-X: heteronuclear multidimensional transferred nuclear overhauser effect analysis of peptide uniformly enriched with 13C and 15N."; Biochemistry 37:4782-4790(1998). |