iVenomDB

Basic info

Organism	Apis mellifera
Taxonomy	Insecta > Hymenoptera > Apidae > Apis > Apis mellifera
Protein Description	Venom serine protease 34 precursor
Mass Weight	45516.09 Da
Isoelectric Point	8.64
Expression	Highly expressed in venom gland

Annotation

Pfam

PF00089

Trypsin

Features

Feature key	Position	Length
Signal Peptide	1..35	35
Chain	36..405	370

Cross-Reference

NCBI Nucleotide	NM_001011584.1
NCBI Protein	NP_001011584.1
UniProt	Q8MQS8

Sequence

CDS[Download]

ATGATTTTCACAAACAATATCGCAGCGTTTCAAAATGTTGTTTTGGTAAAAAAAGTTAAGATAGTGTTGTTAATATTCTATGGATCAATTATGTTTTCTATGACTCAAGTAAATAAGGAAGAATGCGACTATTATCAAAACCTAAATCTTGGCGAAATATATTATATTTACAATCCTAGATATCCATTACCATACTCTGGATCAAAATGTACATGGACTATCACAAGTTATCATCGAATTAATTTAAAGTGTTCCTTAGTTGAATTTTCAGAAAATAAAAATTGCAACGCAGGCAGTTTAACTGTTAAAAAGAATTTCGCTAACAAATATTGTGGTAATATAACATTGAATATAGAATCCACATCAAATAAAATGACTGTAATACTAACACCACCAGGTAGATTTTTCTGTGAAGTACGACCAATAAAAAGAGTAAAAGATTCTACAAATTGTAATTGTGGATGGAAAAATCCTTCTAGAATCGTTGGTGGAACTAATACAGGAATAAATGAATTTCCTATGATGGCTGGTATTAAACGCACTTATGAACCTGGCATGATTTGTGGAGCTACTATAATATCCAAACGATATGTATTAACAGCAGCACATTGCATCATAGATGAGAATACTACAAAATTAGCTATCGTAGTTGGTGAACATGATTGGAGCAGTAAAACAGAAACAAACGCCACAGTATTGCATAGCATTAATAAAGTTATTATACATCCAAAGTATGACATCATAGAAAAGGATGATTGGCAAATAAACGATATAGCACTTTTGAAAACAGAAAAAGATATTAAATTTGGCGACAAGGTTGGACCTGCTTGTCTACCTTTTCAACATTTTTTAGATTCTTTTGCTGGTTCTGATGTTACTGTATTGGGTTGGGGTCATACGAGTTTTAACGGTATGCTTTCTCATATTTTGCAAAAAACTACATTAAATATGCTTACACAAGTAGAATGTTATAAATATTATGGCAATATAATGGTTAACGCAATGTGTGCTTATGCAAAAGGCAAGGATGCGTGTCAGATGGATAGTGGTGGACCAGTTCTATGGCAAAATCCTCGAACTAAACGACTCGTAAACATAGGAATTATCAGTTGGGGTGCAGAGTGTGGTAAATATCCAAATGGTAATACAAAAGTTGGTTCTTATATAGATTGGATCGTTTCACAAACTCCAGATGCTGAATATTGTGTCATCGAATAA

Protein[Download]

MIFTNNIAAFQNVVLVKKVKIVLLIFYGSIMFSMTQVNKEECDYYQNLNLGEIYYIYNPRYPLPYSGSKCTWTITSYHRINLKCSLVEFSENKNCNAGSLTVKKNFANKYCGNITLNIESTSNKMTVILTPPGRFFCEVRPIKRVKDSTNCNCGWKNPSRIVGGTNTGINEFPMMAGIKRTYEPGMICGATIISKRYVLTAAHCIIDENTTKLAIVVGEHDWSSKTETNATVLHSINKVIIHPKYDIIEKDDWQINDIALLKTEKDIKFGDKVGPACLPFQHFLDSFAGSDVTVLGWGHTSFNGMLSHILQKTTLNMLTQVECYKYYGNIMVNAMCAYAKGKDACQMDSGGPVLWQNPRTKRLVNIGIISWGAECGKYPNGNTKVGSYIDWIVSQTPDAEYCVIE

3D Structure

Alphafold Prediction

Publication

1.	Schmidt M., Winningham K.M., Hoffman D.R.; "The bee venom protease allergen contains a CUB domain."; J. Allergy Clin. Immunol. 109:S79-S79(2002).
2.	"Insights into social insects from the genome of the honeybee Apis mellifera."; Nature 443:931-949(2006).

Venom Protein Card