Venom Protein Card


Accession: Pre05378    Preproapamin   [Apis cerana]

Basic info
Organism Apis cerana
Taxonomy Insecta > Hymenoptera > Apidae > Apis > Apis cerana
Protein Description Preproapamin
Mass Weight 5107.18 Da
Isoelectric Point 8.79
Expression Highly expressed in venom gland
Annotation
Function Neurotoxin that blocks voltage-independent calcium-activated potassium channels (KCNN1=SK1, KCNN2=SK2, KCNN3=SK3).
Pfam
PF17454 Bee_toxin
Features
Feature key Position Length
Signal Peptide 1..27 27
Peptide 28..45 18
Cross-Reference
NCBI Nucleotide AY164489.1
NCBI Protein AAO19578.1
UniProt Q86QT2
Sequence
ATGATTTCTATGCTGAGATGCATTTCCTTATTTTTATCTGTTATTTTAATAACAGGCTACTTTGTGACACCAGTAATGTCCTGTAATTGTAAAGCACCAGAAACTGCACTTTGCGCAAGACGTTGTCAACAGCATGGATAA
MISMLRCISLFLSVILITGYFVTPVMSCNCKAPETALCARRCQQHG

3D Structure
Publication
1. Zhang S.F., Shi W.J., Cheng J.A., Zhang C.X.;
"Cloning and comparison of the genes encoding precursor of apamin from the venom of honeybees and wasps."; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.