iVenomDB

Venom Protein Card

Accession: Pre05399 Kazal-type serine protease inhibitor [Apis cerana]

Basic info

Organism	Apis cerana
Taxonomy	Insecta > Hymenoptera > Apidae > Apis > Apis cerana
Protein Description	Kazal-type serine protease inhibitor
Mass Weight	14170.9 Da
Isoelectric Point	5.68
Expression	Highly expressed in venom gland

Annotation

Function

Kazal-type serine protease inhibitor (AcKTSPI) that acts as a microbial serine protease inhibitor was identified.

Pfam

PF00050

Kazal_1

Features

Feature key	Position	Length
Signal Peptide	1..17	17
Chain	18..128	111

Cross-Reference

NCBI Nucleotide	KF219696.1
NCBI Protein	AGW24880.1
UniProt	U3N283

Sequence

CDS[Download]

ATGTGGTTTTTTCTAATATTAGCTATTGCTGCGAATAGGAATGTAATCGCATTTCCACAGAATGACTTGAGCGATAACAATATTGAGATTCAAACGCTACCTACCACATTCGAAGTAGATGGATTTATTTTTGATGGACCAGCAAATAGACCATTACGGCAAACTTCCACAATTATAACAACTACTACTACAGCAGCTACAGTTGATCCTCAATTCGATCAATGTGTTGCAACATGTCGGACGACACCCGAATATAATCCTGTATGTGGAACAGACCAAATCGACTATAAAAATCCTGGGCAACTAAGCTGTGCATCTATGTGTGGAAAAGATGTTTCATTAAAACATTATGGACGTTGCACGACTACGAAAATAAGAGGAAGATAA

Protein[Download]

MWFFLILAIAANRNVIAFPQNDLSDNNIEIQTLPTTFEVDGFIFDGPANRPLRQTSTIITTTTTAATVDPQFDQCVATCRTTPEYNPVCGTDQIDYKNPGQLSCASMCGKDVSLKHYGRCTTTKIRGR

3D Structure

Alphafold Prediction

Publication

1.	Kim B.Y., Lee K.S., Zou F.M., Wan H., Choi Y.S., Yoon H.J., Kwon H.W., Je Y.H., Jin B.R.; "Antimicrobial activity of a honeybee (Apis cerana) venom Kazal-type serine protease inhibitor."; Toxicon 76:110-117(2013).
2.	Kim B.Y., Lee K.S., Choi Y.S., Yoon H.J., Jin B.R.; "Antimicrobial activity of a honeybee (Apis cerana) venom Kazal-type serine protease inhibitor."; Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.